Enhancement of dissolution rate of Clofibrate BCS Class –II drug by using liquisolid compact technology
نویسندگان
چکیده
منابع مشابه
Emerging Liquisolid Compact Technology for Solubility Enhancement of BCS Class-II Drug
Diazepam possesses potent anti-epileptic, anti-anxiety activity and also indicated for the treatment of insomnia. It is very slightly soluble in water and shows poor dissolution. Presently, liquisolid compact technique is found to be used extensively as one of the successful tool to enhance the solubility and dissolution of various poorly soluble drugs. The principle focus of this study is to f...
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Purpose: The aim of present study was to improve the dissolution rate of poorly soluble drug Loperamide (LPM) by liquisolid compact technique. Methods: Liquisolid compacts of LPM were prepared using Propylene glycol (PG) as a solvent, Avicel pH 102 as carrier, Aerosil as coating material and Sodium Starch Glycolate (SSG) as superdisintegrant. Interactions between the drug and excipients were ex...
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ژورنال
عنوان ژورنال: International Journal of Biomedical and Advance Research
سال: 2015
ISSN: 2229-3809
DOI: 10.7439/ijbar.v6i3.1891